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1

Pattern of nucleotide variants of TP53 and their correlation with the expression of p53 and its downstream proteins in a Sri Lankan cohort of breast and colorectal cancer patients

Manoharan, Vahinipriya, Karunanayake, Eric Hamilton, Tennekoon, Kamani Hemamala, De Silva, Sumadee, Imthikab, Ahamed Ilyas Ahamed, De Silva, Kanishka, Angunawela, Preethika, Vishwakula, Sameera, Lunec

Journal:

Year:

2020

Language:

english

File:

PDF, 1.89 MB

english, 2020

2

Non-glucose metabolism in cancer cells—is it all in the fat?

Biswas, Swethajit, Lunec, John, Bartlett, Kim

Journal:

Cancer and Metastasis Reviews

Year:

2012

Language:

english

File:

PDF, 595 KB

english, 2012

3

Of dogs and men: Comparative biology as a tool for the discovery of novel biomarkers and drug development targets in osteosarcoma

Kenneth S. Rankin, Mike Starkey, John Lunec, Craig H. Gerrand, Sue Murphy, Swethajit Biswas

Journal:

Pediatric Blood & Cancer

Year:

2012

Language:

english

File:

PDF, 141 KB

english, 2012

4

The molecular pathology of p53 in primitive neuroectodermal tumours of the central nervous system

Burns, A S Y W, Jaros, E, Cole, M, Perry, R, Pearson, A J, Lunec, J

Journal:

British Journal of Cancer

Year:

2002

Language:

english

File:

PDF, 508 KB

english, 2002

5

Deoxycytidine glyoxal: lesion induction and evidence of repair following vitamin C supplementation in vivo

Marcus S Cooke, Nalini Mistry, Jabeen Ahmad, Helen Waller, Lynda Langford, Ruth J Bevan, Mark D Evans, George D.D Jones, Karl E Herbert, Helen R Griffiths, Joseph Lunec

Journal:

Free Radical Biology and Medicine

Year:

2003

Language:

english

File:

PDF, 215 KB

english, 2003

6

The MYCN oncoprotein as a drug development target

Xiaohong Lu, Andrew Pearson, John Lunec

Journal:

Year:

2003

Language:

english

File:

PDF, 155 KB

english, 2003

7

Induction of thymidylate synthase as a 5-fluorouracil resistance mechanism

G.J Peters, H.H.J Backus, S Freemantle, B van Triest, G Codacci-Pisanelli, C.L van der Wilt, K Smid, J Lunec, A.H Calvert, S Marsh, H.L McLeod, E Bloemena, S Meijer, G Jansen, C.J van Groeningen, H.M

Journal:

Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease

Year:

2002

Language:

english

File:

PDF, 233 KB

english, 2002

8

Cell cycle and dose-dependence of DNA damage and p53 expression following UVA irradiation

COOKE, MARCUS S., FINNEGAN, MONICA T., HERBERT, KARL E., LUNEC, JOSEPH

Journal:

Biochemical Society Transactions

Year:

1995

Language:

english

File:

PDF, 108 KB

english, 1995

9

Characterization and drug sensitivity of a novel human ovarian clear cell carcinoma cell line genomically and phenotypically similar to the original tumor

Franklin, Miriam, Gentles, Lucy, Matheson, Elizabeth, Bown, Nick, Cross, Paul, Ralte, Angela, Gilkes-Immeson, Connor, Bradbury, Alice, Zanjirband, Maryam, Lunec, John, Drew, Yvette, O'Donnell, Rachel,

Journal:

Cancer Medicine

Year:

2018

Language:

english

File:

PDF, 982 KB

english, 2018

10

Molecular cytogenetic delineation of 17q translocation breakpoints in neuroblastoma cell lines

Maria |fLastowska, Nadine Van Roy, Nick Bown, Frank Speleman, John Lunec, Tom Strachan, Andrew D. J. Pearson, Michael S. Jackson

Journal:

Genes, Chromosomes and Cancer

Year:

1998

Language:

english

File:

PDF, 408 KB

english, 1998

11

Molecular cytogenetic definition of 17q translocation breakpoints in neuroblastoma

M. Łastowska, N. Van Roy, N. Bown, F. Speleman, P. Roberts, J. Lunec, T. Strachan, A.D.J. Pearson, M.S. Jackson

Journal:

Pediatric Blood & Cancer

Year:

2001

Language:

english

File:

PDF, 85 KB

english, 2001

12

Relationship between histopathological features, MYCN amplification, and prognosis: A UKCCSG study

R.E. George, S. Variend, C. Cullinane, S.J. Cotterill, A.G. McGuckin, C. Ellershaw, J. Lunec, A.D.J. Pearson

Journal:

Pediatric Blood & Cancer

Year:

2001

Language:

english

File:

PDF, 138 KB

english, 2001

13

Breakpoint position on 17q identifies the most aggressive neuroblastoma tumors

Maria Łastowska, Simon Cotterill, Nick Bown, Catherine Cullinane, Sadick Variend, John Lunec, Tom Strachan, Andrew D.J. Pearson, Michael S. Jackson

Journal:

Genes, Chromosomes and Cancer

Year:

2002

Language:

english

File:

PDF, 208 KB

english, 2002

14

Novel ERBB4 juxtamembrane splice variants are frequently expressed in childhood medulloblastoma

Richard Gilbertson, Roberto Hernan, Torsten Pietsch, Lais Pinto, Paul Scotting, Richard Allibone, David Ellison, Robert Perry, Andrew Pearson, John Lunec

Journal:

Genes, Chromosomes and Cancer

Year:

2001

Language:

english

File:

PDF, 160 KB

english, 2001

15

Analysis of the p53 tumor-suppressor gene in hepatocellular carcinomas from britain

Christine Challen, John Lunec, William Warren, Jane Collier, Dr. Margaret F. Bassendine

Journal:

Year:

1992

Language:

english

File:

PDF, 530 KB

english, 1992

16

DNA repair and repair fidelity in metastatic variants of the B16 murine melanoma

B. A. Usmani, J. Lunec, G. V. Sherbet

Journal:

Journal of Cellular Biochemistry

Year:

1993

Language:

english

File:

PDF, 768 KB

english, 1993

17

Analysis of internucleosomal DNA fragmentation in apoptotic thymocytes by dynamic sieving capillary electrophoresis

Mark D. Evans, James T. Wolfe, David Perrett, Joseph Lunec, Karl E. Herbert

Journal:

Journal of Chromatography A

Year:

1995

Language:

english

File:

PDF, 777 KB

english, 1995

18

Probing molecular changes induced in DNA by reactive oxygen species with monoclonal antibodies

S. Blount, H.R. Griffiths, N.A. Staines, J. Lunec

Journal:

Immunology Letters

Year:

1992

Language:

english

File:

PDF, 676 KB

english, 1992

19

P53 overexpression in head and neck carcinoma and radiotherapy results

Saif Awwad, Evelyn Jaros, James Somes, John Lunec

Journal:

International Journal of Radiation Oncology*Biology*Physics

Year:

1996

Language:

english

File:

PDF, 6.59 MB

english, 1996

20

Fluorescent malondialdehyde polymers from hydrolysed 1,1,3,3-tetramethoxypropane

J.M.C. Gutteridge, A.D. Heys, J. Lunec

Journal:

Analytica Chimica Acta

Year:

1977

Language:

english

File:

PDF, 256 KB

english, 1977

21

Combined p21WAF1/CIP1 and p53 overexpression predict improved survival in muscle-invasive bladder cancer treated by radical radiotherapy

K.N Qureshi, T.R.L Griffiths, M.C Robinson, C Marsh, J.T Roberts, J Lunec, D.E Neal, J.K Mellon

Journal:

International Journal of Radiation Oncology*Biology*Physics

Year:

2001

Language:

english

File:

PDF, 71 KB

english, 2001

22

Analysis of the N-myc amplicon in neuroblastoma

R.M. Kenyon, R.E. George, A.G. McGuckin, A.D.J. Pearson, J. Lunec

Journal:

Clinical Oncology

Year:

1996

Language:

english

File:

PDF, 158 KB

english, 1996

23

Investigation of coamplification of the candidate genes ornithine decarboxylase, ribonucleotide reductase, syndecan-1 and a dead box gene, DDX1, in neuroblastoma

R.E. George, R. Kenyon, A.G. McGuckin, A.J. Malcolm, A.D.J. Pearson, J. Lunec

Journal:

Clinical Oncology

Year:

1996

Language:

english

File:

PDF, 290 KB

english, 1996

24

Expression of cyclin-dependent kinase inhibitor p21(WAF1) and p53 tumour suppressor gene in laryngeal cancer

J.-P. Jeannon, J. Soames, J. Lunec, S. Awwad, V. Ashton, J. A. Wilson

Journal:

Clinical Otolaryngology (Blackwell)

Year:

2000

Language:

english

File:

PDF, 325 KB

english, 2000

25

Expression of cyclin-dependent kinase inhibitor p21(WAFI) and p53 tumour suppressor gene in laryngeal cancer

J.-P. Jeannon, J. Soames, J. Lunec, S. Awwaad, V. Ashton, J.A. Wilson

Journal:

Clinical Otolaryngology (Blackwell)

Year:

2000

File:

PDF, 68 KB

2000

26

Nuclear to cytoplasmic compartment shift of the p33ING1b tumour suppressor protein is associated with malignancy in melanocytic lesions

G S Nouman, J J Anderson, M E Mathers, N Leonard, S Crosier, J Lunec, B Angus

Journal:

Year:

2002

Language:

english

File:

PDF, 253 KB

english, 2002

27

p53 and p53-regulated genes in bladder cancer

Keegan, Lunec, Neal

Journal:

BJU International

Year:

1998

Language:

english

File:

PDF, 240 KB

english, 1998

28

Statistical problems with ‘optimal’ thresholds in studies of new prognostic factors in urology

P.E. Keegan, J.N.S. Matthews, J. Lunec, D.E. Neal

Journal:

BJU International

Year:

2000

Language:

english

File:

PDF, 79 KB

english, 2000

29

Matrix metalloproteinases (MMPs) in bladder cancer: the induction of MMP9 by epidermal growth factor and its detection in urine

J.E. Nutt, G.C. Durkan, J.K. Mellon, J. Lunec

Journal:

BJU International

Year:

2003

Language:

english

File:

PDF, 142 KB

english, 2003

30

Induction and Excretion of Ultraviolet-Induced 8-Oxo-2'-deoxyguanosine and Thymine Dimers In Vivo: Implications for PUVA

Cooke, Marcus S., Evans, Mark D., Burd, Robert M., Patel, Kayuri, Barnard, Angela, Lunec, Joseph, Hutchinson, Peter E.

Journal:

The Journal of Investigative Dermatology

Year:

2001

Language:

english

File:

PDF, 156 KB

english, 2001

31

Analysis of the MDM2 antagonist nutlin-3 in human prostate cancer cells

Ian R. Logan, Hesta V. McNeill, Susan Cook, Xiaohong Lu, John Lunec, Craig N. Robson

Journal:

Year:

2007

Language:

english

File:

PDF, 283 KB

english, 2007

32

The expression of functional MSH receptors on cultured human melanocytes

P. D. Donatien, G. Hunt, C. Pieron, J. Lunec, A. TaÏeb, A. J. Thody

Journal:

Archives of Dermatological Research

Year:

1992

Language:

english

File:

PDF, 323 KB

english, 1992

33

Disturbed handling of ascorbic acid in diabetic patients with and without microangiopathy during high dose ascorbate supplementation

A. J. Sinclair, A. J. Girling, L. Gray, C. Le Guen, J. Lunec, A. H. Barnett

Journal:

Year:

1991

Language:

english

File:

PDF, 591 KB

english, 1991

34

In vivo monitoring of serum protein cross linking in patients with diabetes mellitus. Evidence for pharmacological modification of immunoglobulin G cross links

B. Lubec, M. Weninger, C. Popow, H. Vierhapper, J. Lunec, G. Lubec

Journal:

Year:

1993

Language:

english

File:

PDF, 933 KB

english, 1993

35

Oxygen radical induced fluorescence in proteins; identification of the fluorescent tryptophan metabolite, N-formyl kynurenine, as a biological index of radical damage

H. R. Griffiths, J. Lunec, D. R. Blake

Journal:

Year:

1992

Language:

english

File:

PDF, 762 KB

english, 1992

36

Meeting report: Free radicals, cell damage and disease

Michael J. Parnham, Joseph Lunec

Journal:

Inflammation Research

Year:

1986

Language:

english

File:

PDF, 219 KB

english, 1986

37

Free-radical-mediated aggregation of human IgG stimulates neutrophils to generate superoxide radicals

Journal:

Inflammation Research

Year:

1984

Language:

english

File:

PDF, 170 KB

english, 1984

38

Selective lymphocyte killing by reactive oxygen species (ROS)

I. M. Allan, J. Lunec, M. Salmon, P. A. Bacon

Journal:

Inflammation Research

Year:

1986

Language:

english

File:

PDF, 135 KB

english, 1986

39

Free-radical mediated aggregation of human gamma-globulin

D. G. Wickens, T. L. Graff, J. Lunec, T. L. Dormandy

Journal:

Inflammation Research

Year:

1981

Language:

english

File:

PDF, 162 KB

english, 1981

40

The selective protection afforded by ebselen against lipid peroxidation in an ROS-dependent model of inflammation

H. R. Griffiths, E. J. Dowling, T. Sahinoglu, D. R. Blake, M. Parnham, J. Lunec

Journal:

Inflammation Research

Year:

1992

Language:

english

File:

PDF, 389 KB

english, 1992

41

Action of free radical generating systems upon the biological and immunological properties of caeruloplasmin

Paul Winyard, Joe Lunec, Sue brailsford, David Blake

Journal:

International Journal of Biochemistry

Year:

1984

Language:

english

File:

PDF, 739 KB

english, 1984

42

Binding of anti-DNA antibodies to oxidatively damaged DNA in spouses and relatives of patients with systemic lupus erythematosus

S. Blount, J. Lunec, H. Griffiths, K. Herbert, D. Isenberg

Journal:

Immunology Letters

Year:

1994

Language:

english

File:

PDF, 282 KB

english, 1994

43

Reactive oxygen species modify human DNA, eliciting a more discriminating antigen for the diagnosis of systemic lupus erythematosus

S. BLOUNT, H. GRIFFITHS, P. EMERY, J. LUNEC

Journal:

Clinical & Experimental Immunology

Year:

1990

Language:

english

File:

PDF, 2.19 MB

english, 1990

44

The predictive value of p53 and p33ING1b in patients with Dukes'C colorectal cancer

I. A. M. Ahmed, S. B. Kelly, J. J. Anderson, B. Angus, C. Challen, J. Lunec

Journal:

Colorectal Disease

Year:

2008

Language:

english

File:

PDF, 388 KB

english, 2008

45

Cultured Human Melanocytes Respond to MSH Peptides and ACTH

GILLIAN HUNT, PHILIPPE D. DONATIEN, JOHN LUNEC, CAROLE TODD, SYLVIA KYNE, ANTHONY J. THODY

Journal:

Pigment Cell & Melanoma Research

Year:

1994

Language:

english

File:

PDF, 568 KB

english, 1994

46

10.1038/26143

Podmore, Ian D., Griffiths, Helen R., Herbert, Karl E., Mistry, Nalini, Mistry, Pratibha, Lunec, Joseph

Journal:

Year:

1998

Language:

english

File:

PDF, 256 KB

english, 1998

47

10.1038/26141

Podmore, Ian D., Griffiths, Helen R., Herbert, Karl E., Mistry, Nalini, Mistry, Pratibha, Lunec, Joseph

Journal:

Year:

1998

Language:

english

File:

PDF, 132 KB

english, 1998

48

10.1038/26146

Podmore, Ian D., Griffiths, Helen R., Herbert, Karl E., Mistry, Nalini, Mistry, Pratibha, Lunec, Joseph

Journal:

Year:

1998

Language:

english

File:

PDF, 96 KB

english, 1998

49

10.1038/26152

Podmore, Ian D., Griffiths, Helen R., Herbert, Karl E., Mistry, Nalini, Mistry, Pratibha, Lunec, Joseph

Journal:

Year:

1998

Language:

english

File:

PDF, 277 KB

english, 1998

50

10.1038/26150

Podmore, Ian D., Griffiths, Helen R., Herbert, Karl E., Mistry, Nalini, Mistry, Pratibha, Lunec, Joseph

Journal:

Year:

1998

Language:

english

File:

PDF, 320 KB

english, 1998